Chung-I Wu

Publications
  1. Lu J, Shen Y, Carthew RW, Wang SM, Wu CI. Reply to evolutionary flux of canonical microRNAs and mirtrons in Drosophila. Nat Genet. 2010 Jan; 42(1):9-10. View in: PubMed

  2. Hungate EA, Earley EJ, Boussy IA, Turissini DA, Ting CT, Moran JR, Wu ML, Wu CI, Jones CD. A locus in Drosophila sechellia affecting tolerance of a host plant toxin. Genetics. 2013 Nov; 195(3):1063-75. View in: PubMed

  3. Zheng C, Miao X, Li Y, Huang Y, Ruan J, Ma X, Wang L, Wu CI, Cai J. Determination of genomic copy number alteration emphasizing a restriction site-based strategy of genome re-sequencing. Bioinformatics. 2013 Nov 15; 29(22):2813-21. View in: PubMed

  4. Wu CI, Shen Y, Tang T. Evolution under canalization and the dual roles of microRNAs: a hypothesis. Genome Res. 2009 May; 19(5):734-43. View in: PubMed

  5. Wu Q, Kim YC, Lu J, Xuan Z, Chen J, Zheng Y, Zhou T, Zhang MQ, Wu CI, Wang SM. Poly A- transcripts expressed in HeLa cells. PLoS One. 2008 Jul 30; 3(7):e2803. View in: PubMed

  6. Lu J, Fu Y, Kumar S, Shen Y, Zeng K, Xu A, Carthew R, Wu CI. Adaptive evolution of newly emerged micro-RNA genes in Drosophila. Mol Biol Evol. 2008 May; 25(5):929-38. View in: PubMed

  7. Lu J, Shen Y, Wu Q, Kumar S, He B, Shi S, Carthew RW, Wang SM, Wu CI. The birth and death of microRNA genes in Drosophila. Nat Genet. 2008 Mar; 40(3):351-5. View in: PubMed

  8. Zeng K, Shi S, Wu CI. Compound tests for the detection of hitchhiking under positive selection. Mol Biol Evol. 2007 Aug; 24(8):1898-908. View in: PubMed

  9. Zeng K, Mano S, Shi S, Wu CI. Comparisons of site- and haplotype-frequency methods for detecting positive selection. Mol Biol Evol. 2007 Jul; 24(7):1562-74. View in: PubMed

  10. Shapiro JA, Huang W, Zhang C, Hubisz MJ, Lu J, Turissini DA, Fang S, Wang HY, Hudson RR, Nielsen R, Chen Z, Wu CI. Adaptive genic evolution in the Drosophila genomes. Proc Natl Acad Sci U S A. 2007 Feb 13; 104(7):2271-6. View in: PubMed

  11. Zeng K, Fu YX, Shi S, Wu CI. Statistical tests for detecting positive selection by utilizing high-frequency variants. Genetics. 2006 Nov; 174(3):1431-9. View in: PubMed

  12. Osada N, Kohn MH, Wu CI. Genomic inferences of the cis-regulatory nucleotide polymorphisms underlying gene expression differences between Drosophila melanogaster mating races. Mol Biol Evol. 2006 Aug; 23(8):1585-91. View in: PubMed

  13. Greenberg AJ, Moran JR, Wu CI. Proper control of genetic background with precise allele substitution: a comment on Coyne and Elwyn. Evolution. 2006 Mar; 60(3):623-5; discussion 626-7. View in: PubMed

  14. Lu J, Tang T, Tang H, Huang J, Shi S, Wu CI. The accumulation of deleterious mutations in rice genomes: a hypothesis on the cost of domestication. Trends Genet. 2006 Mar; 22(3):126-31. View in: PubMed

  15. Greenberg AJ, Wu CI. Proceedings of the SMBE Tri-National Young Investigators' Workshop 2005. Molecular genetics of natural populations. Mol Biol Evol. 2006 May; 23(5):883-6. View in: PubMed

  16. Greenberg AJ, Moran JR, Fang S, Wu CI. Adaptive loss of an old duplicated gene during incipient speciation. Mol Biol Evol. 2006 Feb; 23(2):401-10. View in: PubMed

  17. Tang H, Wu CI. A new method for estimating nonsynonymous substitutions and its applications to detecting positive selection. Mol Biol Evol. 2006 Feb; 23(2):372-9. View in: PubMed

  18. Lee S, Bao J, Zhou G, Shapiro J, Xu J, Shi RZ, Lu X, Clark T, Johnson D, Kim YC, Wing C, Tseng C, Sun M, Lin W, Wang J, Yang H, Wang J, Du W, Wu CI, Zhang X, Wang SM. Detecting novel low-abundant transcripts in Drosophila. RNA. 2005 Jun; 11(6):939-46. View in: PubMed

  19. Alipaz JA, Karr TL, Wu CI. Evolution of sexual isolation in laboratory populations: fitness differences between mating types and the associated hybrid incompatibilities. Am Nat. 2005 Apr; 165(4):429-38. View in: PubMed

  20. Alipaz JA, Fang S, Osada N, Wu CI. Evolution of sexual isolation during secondary contact: genotypic versus phenotypic changes in laboratory populations. Am Nat. 2005 Apr; 165(4):420-8. View in: PubMed

  21. Lu J, Wu CI. Weak selection revealed by the whole-genome comparison of the X chromosome and autosomes of human and chimpanzee. Proc Natl Acad Sci U S A. 2005 Mar 15; 102(11):4063-7. View in: PubMed

  22. Osada N, Wu CI. Inferring the mode of speciation from genomic data: a study of the great apes. Genetics. 2005 Jan; 169(1):259-64. View in: PubMed

  23. Sun S, Ting CT, Wu CI. The normal function of a speciation gene, Odysseus, and its hybrid sterility effect. Science. 2004 Jul 02; 305(5680):81-3. View in: PubMed

  24. Tang H, Wyckoff GJ, Lu J, Wu CI. A universal evolutionary index for amino acid changes. Mol Biol Evol. 2004 Aug; 21(8):1548-56. View in: PubMed

  25. Wu CI, Shi S, Zhang YP. A case for conservation. Nature. 2004 Mar 11; 428(6979):213-4. View in: PubMed

  26. Wu CI, Ting CT. Genes and speciation. Nat Rev Genet. 2004 Feb; 5(2):114-22. View in: PubMed

  27. Kohn MH, Fang S, Wu CI. Inference of positive and negative selection on the 5' regulatory regions of Drosophila genes. Mol Biol Evol. 2004 Feb; 21(2):374-83. View in: PubMed

  28. Greenberg AJ, Moran JR, Coyne JA, Wu CI. Ecological adaptation during incipient speciation revealed by precise gene replacement. Science. 2003 Dec 05; 302(5651):1754-7. View in: PubMed

  29. Lu J, Li WH, Wu CI. Comment on "Chromosomal speciation and molecular divergence-accelerated evolution in rearranged chromosomes". Science. 2003 Nov 07; 302(5647):988; author reply 988. View in: PubMed

  30. Wu CI, Xu EY. Sexual antagonism and X inactivation--the SAXI hypothesis. Trends Genet. 2003 May; 19(5):243-7. View in: PubMed

  31. Fang S, Takahashi A, Wu CI. A mutation in the promoter of desaturase 2 is correlated with sexual isolation between Drosophila behavioral races. Genetics. 2002 Oct; 162(2):781-4. View in: PubMed

  32. Fay JC, Wyckoff GJ, Wu CI. Testing the neutral theory of molecular evolution with genomic data from Drosophila. Nature. 2002 Feb 28; 415(6875):1024-6. View in: PubMed